Inter-organelle Stress Communication in Inflammation & Disease Conference
Organiser: Other
Attendance type(s): In Person
Event Dates: 10—13 Oct 2025
- 10/10/2025
- 13/10/2025
Registration Deadline: 14 Aug 2025
Stress responses require proper communication and orchestration between organelles critical for key decisions in cell survival and death, and crosstalk between networks is required to properly join stress responses with metabolic pathways compartmentalized within distinct organelles. Dysregulated organelle networks are increasingly implicated in cell and tissue dysfunction governing disease mechanisms, including inflammation. For example, the inability of nuclear DNA repair proteins to localize to and act on mitochondrial DNA elicits the release of damage-associated molecular patterns (DAMPs) that trigger inflammatory signalling cascades. Similarly, lysosomal dysfunction can perturb mitochondrial activity, leading to metabolic impairment and DAMP-induced inflammation. This interdisciplinary meeting will bring together experts working on genome instability, organelle biology and immunity to advance understanding of organelle stress communication mechanisms in homeostatic and pathological settings including cancer, metabolic and neurologic diseases, and aging.
Key Sessions:
• Mitochondria-Nuclear Crosstalk in DNA Damage Responses
• Mitochondria-ER-Lysosome Crosstalk and Quality Control
• DNA Damage Responses and Inflammation
• Organelles in Innate Immune Signalling
• Organelle Communication in Metabolic and Inflammatory Diseases
• Organelle Communication in Neurodegeneration and Aging
• Organelle Communication in Cancer
Important Dates:
Early bird – 01 may 2025
Talk Submission – 01 May 2025
Poster Submission – 14 August 2025
Registration Closes – 14 August 2025
Contact Details
Name: Chloe Trundle
Address: Unit 5D Lynx Business Pk, Newmarket CB8 7NY UK
Email: admin@fusion-conferences.com