Massimo Mantegazza

CountryFrance

Society affiliation Société des Neurosciences

ORCID ID ORCID iD 0000-0002-1070-7929

Position Principal Investigator/Group Leader

University/Organisation Institut de Pharmacologie Moléculaire et Cellulaire (IPMC)

Domain Other Brain Diseases, Ischemia, Stroke, Injury

Sub domains Action potentials Epilepsy Ion channels

Lab description

We are interested in how ion channels shape neuronal functions (in particular excitability), in how they are modulated or blocked by drugs and toxins and in how their modifications (e.g. mutations) cause pathologies, trying to disclose the complex responses produced by the initial dysfunction. A major focus are voltage gated Na+ (Nav) channels and their involvement in the pathophysiology of epilepsy, migraine and neuro-developmental disorders . We also develop innovative strategies for the treatment of pathological cellular excitability.

Lab URLhttps://www.ipmc.cnrs.fr/?page=mantegazza&lang=uk