Job ID: 122622

Postdoc & PhD in Neuronal cytoskeleton

Position: PostDOc and PhD positions

Deadline: 31 May 2025

Employment Start Date: 5 May 2025

Contract Length: 2 to 3 years

City: Lyon

Country: France

Institution: INMG-PGNM

Department:

Description:

We are seeking highly motivated candidates for neuronal cytoskeleton, to work on a project aiming at fueling innovation in fundamental neurobiology and therapeutic development.

Science. Major cytoskeletal component of neurons, Neurofilaments (NFs) provide the structural scaffold of axons and exhibit important functions throughout the nervous system (review in Curr Opin Cell Biol 2024: http://doi.org/10.1016/j.ceb.2024.102326). Important for physiology, NF genes are mutated in several peripheral neuropathies, producing mutant-NF aggregation that is shared by most neurodegenerative diseases in human (review in Front Cell Dev Biol. 2023: http://doi.org/10.3389/fcell.2023.1275155). With such fundamental and clinical significance, our project aims at decoding the roles of NFs in vivo in a physiological environment, using the zebrafish model. This project has the ambition to decipher the dynamics, regulation and functions of NFs, and to develop new therapeutic avenues for neurodegenerative diseases.

Profiles. 2 to 3-year positions for 1 Post Doctoral researcher and 1 PhD student. Mandatory for all profiles: curious, enthusiastic & team player. Background in neurobiology. We want to recruit candidates with COMPLEMENTARY profiles in zebrafish, OR glial cells, OR advanced live microscopy approaches, OR mathematic modeling applied to biology. Preferred: expertise in cytoskeleton and/or neurodegenerative disorders. French speaking is NOT a requirement.

When/how to apply.

URGENT: starting date ASAP in 2025. Please send your application in a SINGLE 3 page-long pdf, including your CV, summary of your previous research experiences, and contact information of 2-3 references to :