Job ID: 119821

Postdoctoral Research Position in Molecular Genetics of Sleep Disorders

Position: Post-doctoral Position

Deadline: 30 September 2024

Employment Start Date: 1 November 2024

Contract Length: 1 year renewable

City: Lausanne

Country: Switzerland

Institution: University of Lausanne

Department: Department of Biomedical Sciences

Description:

UNIL is a leading international teaching and research institution, with over 5,000 employees and 17,000 students split between its Dorigny campus, CHUV and Epalinges. UNIL encourages excellence, individual recognition and responsibility.

The laboratory of Dr. Anne Vassalli in the Department of Biomedical Sciences is seeking a highly motivated Postdoctoral Associate to lead an exciting research project funded by the Swiss Federal Innovation Agency “Innosuisse”.

Project description

 Our laboratory is interested in understanding the cause of the sleep disorder narcolepsy. Following our recent discovery of epigenetic silencing of the hypocretin/orexin gene in narcolepsy patients, the aim of the project is to provide Proof-of-Concept of the disease reversal by epigenetic drugs. We seek to leverage diverse in vitro (cell-based) and in vivo (mouse model) approaches to identify novel compounds (small molecules) that will reactivate the hypocretin/orexin gene and lead to the development of the first disease-modifying treatment for narcolepsy.

Workplace: University of Lausanne – Bugnon/CHUV

Your responsibilities

  • Plan, direct, and conduct advanced research experiments involving molecular biology and both cellular and mouse model systems.
  • Evaluate and statistically analyze data
  • Summarize research findings and publish results.
  • Work closely with the principal investigator to design and dynamically optimize experimental strategies and directions of the project.

Your qualifications

  • Ph.D. in Life Science involving molecular/cellular neuroscience or neurogenetics.
  • Experience in molecular biology, cell culture, molecular genetics, in vitro and in vivo neuropharmacology.
  • You are a dynamic, dedicated scientist, critical thinker, with a team player spirit. You are keen to develop novel multidisciplinary skills to understand the basic mechanisms of neurological diseases.

What the position offers you

 We offer a nice working place in a multicultural, diverse and dynamic academic environment. Opportunities for professional training, a lot of activities and other benefits to discover.

Contact for further information: Dr Anne Vassalli – anne.vassalli@unil.ch – Phone: 0041 21 692 5540 or 0041 79 669 5619

Your application: Please send your CV, motivation letter and 2 recommendation letters in Word or PDF, preferably as a single document titled with your name, using the link below:

https://career5.successfactors.eu/career?career%5fns=job%5flisting&company=universitdP&navBarLevel=JOB%5fSEARCH&rcm%5fsite%5flocale=en%5fUS&career_job_req_id=21789&selected_lang=en_US&jobAlertController_jobAlertId=&jobAlertController_jobAlertName=&browserTimeZone=Europe/Paris&_s.crb=%2fHBpZvC7kaD14AtRgTJ2HQsjpjhH%2fO1MkRFy%2bdNUV3I%3d

https://news.unil.ch/display/1721635935452

UNIL is committed to equal opportunities and diversity. www.unil.ch/egalite. UNIL supports early career researchers. https://www.unil.ch/welcomecentre/en/home.html